Liga Nacional de Guatemala 2021-2022 Top Goals
| Player | Team |  |
 |
|---|---|---|---|
| Matias Rotondi | Malacateco | 12 | 0 |
| Dewinder Bradley | Nueva Concepcion | 12 | 2 |
| Pedro Baez | Antigua GFC | 8 | 0 |
| Thales Possas | Santa Lucia FC | 8 | 0 |
| Janderson Kione Pereira Rodrigues | Coban Imperial | 6 | 0 |
| Wilber Mauricio Perez Medrano | CSD Municipal | 6 | 0 |
| Anllel de Jesus Porras Conejo | Guastatoya | 6 | 0 |
| Oscar Alexander Santis Cayax | Club Comunicaciones | 6 | 0 |
| Nelso Garcia | Club Comunicaciones | 6 | 0 |
| Harim Quezada | CSD Municipal | 6 | 0 |
